DES MOINES, Iowa – The Drake University women’s golf team opens its spring campaign at the FGCU Eagle Invitational on Friday (Feb. 11) through Sunday (Feb. 14). The 54-hole event hosted by Florida Gulf Coast at the Stoneybrook Golf Club in Estero, Fla. will tee off at 8 a.m. EST each day with a reverse shotgun start. The 14-team field includes; Arkansas State, Ball State, Central Arkansas, Drake, Elon, FAU, FGCU, McNeese State, Mercer, SIU, Stephen F. Austin, Toledo, USC Upstate, Western Illinois and Xavier. The Bulldogs will look to continue where they left off from the fall season as they won the Creighton Classic with sophomore Madison Glennie claiming the individual crown. Glennie entered the final day of the Creighton Classic tied for first with South Dakota’s Brenna Lervick, and fired a tournament-low 72 (E) to finish on top of the leaderboard with a score of 148 (76-72). The rest of the Bulldogs each improved their second round scores by at least six strokes. Freshman Grace Dunn finished tied for eighth with a score of 158 (82-76), while senior Katie Clausen was seven strokes better on the final round than her first round, totaling a 161 (84-77). Freshman Sophie Hill carded an 80 on the final day for a total of 166 (86-80). Freshman Adrianna Elliott rounded out the Bulldogs strong finish with a total score of 174 (90-84). UP NEXT The Bulldogs will play at the Red Rocks Invitational, hosted by Northern Arizona on March 5 through March 6. Print Friendly Version
Neil’s stunning portrait.There have been thousands of pictures taken of iconic Fanad Lighthouse.But Neil Carey’s is up there amongst the best.Neil simply tags his stunning portrait ‘Last moments of daylight as the lamp switches on in Fanad lighthouse.’ THE GUIDING LIGHT IN THE SKYLINE ABOVE FANAD – PICTURE SPECIAL was last modified: August 25th, 2014 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:donegalfanad lighthouseNeil Carey Photography
Steve O’Meara, Gary Corcoran and Mitchell Smith will appear on the undercard of George Groves’ European super-middleweight title fight at Wembley Arena on 16 March.Groves, the Commonwealth champion, will face Mouhamed Ali Ndiaye for the EBU belt recently vacated by his arch-rival and fellow West Londoner James DeGale.And O’Meara (pictured above) will be in action for the first time since an unsuccessful attempt to win the Commonwealth light-middleweight belt in December.The 29-year-old, who was born in Shepherd’s Bush and lives in West Drayton, remains in the hunt for a major title.Welterweight Corcoran, from Wembley, will be looking to extend his unbeaten record, as will Harrow Weald’s super-featherweight prospect Smith.See also:Corcoran easily extends unbeaten record O’Meara suffers defeat in title clash Groves tipped to win world title in 2013Groves set to fight for European title Groves to fight for title at Wembley ArenaGroves lining up world title challengeThe press conference to announce Groves’ Wembley returnTrainer Booth discusses George Groves’ European title fightGroves ready to add European belt to his title collectionGroves warned ahead of title 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 Follow West London Sport on TwitterFind us on Facebook
When Raiders owner Mark Davis said “all options are open” regarding a home site for the 2019 season, he wasn’t kidding.According to Fox Sports NFL insider Jay Glazer Sunday morning,the Raiders and the NFL have discussed the possibility of playing next season with London as their home site. The Daily Mail reported the Raiders are in discussions with English Premier League side Tottenham Hotspur to share their new stadium in London.The Raiders currently don’t have a lease deal to play in …
Remember Lamarck? He was the pre-Darwin evolutionist whose theories we were all taught were overthrown by Darwin’s superior theory of natural selection. Lamarck’s theory of “inheritance of acquired characteristics” was shown to be demonstrably false by the dramatic experiments of Weismann, right? It was never really so clear-cut as that, as evolutionary historians know, but that’s been the common understanding. This week, Nature printed an “Insight Perspectives” article about epigenetics (“above genetics”) that, while not referring to Lamarck by name, discussed “acquired” traits that could be inherited by “non-Mendelian” methods. Its author, Arturas Petronis,1 even spoke of the growing realization of the importance of epigenetics as a new “unifying principle” and a “paradigm shift” in the style of Thomas Kuhn. For a long time since the structure of DNA was elucidated, the “central dogma” of genetics has been that DNA is the master controller of inheritance. Information flows from DNA to proteins, and that dictates the phenotype (the outward form of the organism). In recent decades, the effects of environmental factors onto the genome has become a growing area of research. Proteins are able to “tag” the histone proteins onto which genes are wound, affecting which genes are expressed or repressed. Some of these epigenetic tags can be inherited. Like most dogmas, the central dogma has been an impediment to new ways of scientific thinking, Petronis claims:The nature-versus-nurture debate was one of the most important themes of biomedical science in the twentieth century. Researchers resolved it by conceding that both factors have a crucial role and that phenotypes result from the actions and interactions of both, which often change over time. Most ‘normal’ phenotypes and disease phenotypes show some degree of heritability, a finding that formed the basis for a series of molecular studies of genes and their DNA sequences. In parallel to such genetic strategies, thousands of epidemiological studies have been carried out to identify environmental factors that contribute to phenotypes. In this article, I consider complex, non-Mendelian, traits and diseases, and review the complexities of investigating their aetiology by using traditional – epidemiological and genetic – approaches. I then offer an epigenetic interpretation that cuts through several of the Gordian knots that are impeding progress in these aetiological studies.It has been very difficult to assign cause-and-effect relationships from environmental factors to traits. “Even strong associations between an environmental factor and a disease do not necessarily prove that the environmental factor has caused the disease,” he said. It is even harder to establish environmental factors to inherited traits, he continued. Even a term like heritability can be hard to nail down when talking specifics. Multiple genes become involved, and statistical likelihoods. Nevertheless, traits do become established in populations. For instance, an article on Live Science shows that Tibetans have inherited a trait for hemoglobin that allows them to survive at high altitude. Petronis asks for breaking the gene-centric paradigm: “I argue that taking an epigenetic perspective allows a different interpretation of the irregularities, complexities and controversies of traditional environmental and genetic studies.” He gave some examples of how acquired traits and environmental effects can influence epigenetic tags that are heritable. There is no longer a clear black-and-white distinction between the views of Darwin and Lamarck (neither of whom were mentioned in Petronis’s essay); the situation is now much more complex:In the domain of epigenetics, the line between ‘inherited’ and ‘acquired’ is fuzzy. Stable epigenetic ‘nature’ merges fluidly with plastic epigenetic ‘nurture’. The ratio between inherited and acquired epigenetic influences can vary considerably depending on species, tissue, age, sex, environmental exposure and stochastic epigenetic events, all of which are consistent with empirical observations that heritability is dynamic and not static. Another close link between heritable factors and environmental factors in epigenetic regulation is the observation that exposure to certain environments has effects that, in some cases, are transmitted epigenetically for several generations.In his conclusion, he said that this new perspective has all the trappings of what Thomas Kuhn called a paradigm shift: “handling the same bundle of data as before, but placing them in a new system of relations with one another by giving them a different framework.” It might explain things like sexual dimorphism, parental origin effects, remissions and relapses, intergenerational disease instances, decline of symptoms with age, and other things – questions that an old paradigm would not find interesting, but a new one would. “The considerable theoretical and experimental potential of an epigenetic perspective makes it a strong alternative to the existing research into complex, non-Mendelian, genetics and biology.” he said. “Although the existence of competing theories may create some discomfort, it can also catalyse discoveries and is indicative of a mature scientific field.” Human genetics is not a closed book. Oh, and what would this new paradigm mean for evolutionary theory? Glad you asked. Of all things, Petronis recalled an old quote by Hugo de Vries sometimes paraded with glee by creationists. But by recalling this quote, he left the reader hanging. In the new paradigm, what is the explanation for the arrival of the fittest? All of the ideas that I have discussed here are highly relevant to the understanding of the fundamental principles of evolution. ‘Soft’, epigenetic, inheritance can have a key role in adaptation to environmental changes and can endure for more than a generation. Phenotypic plasticity might stem mainly from the ability of epigenetic genotype (or epigenotype) – rather than genotype – to produce different phenotypes in different environments. Heritable epigenetic variation could explain the faster-than-expected adaptation to environmental change that is often observed in natural populations. In addition, the large intra-individual epigenetic variation in the germ line may shed new light on the problem presented by one of the first geneticists, Hugo De Vries, more than a century ago, in his book Species and Varieties: Their Origin by Mutation, when he wrote “Natural selection may explain the survival of the fittest, but it cannot explain the arrival of the fittest.”Petronis had nothing further to say about fitness or its arrival. Furthermore, despite the title of his paper, “Epigenetics as a unifying principle in the aetiology of complex traits and diseases,” he gave no description of how any specific complex trait might arise by genetics, by epigenetics, or by any combination of the two. He only said that a new paradigm shift might “shed light” on the problem presented by Hugo De Vries a century ago.1. Arturas Petronis, “Epigenetics as a unifying principle in the aetiology of complex traits and diseases,” Nature 465, pp 721-727, 10 June 2010, doi:10.1038/nature09230.That Nature would let in the ghost of Lamarck is a sign of their desperation with Darwin. So here we are a century after Hugo, waiting for some light. Petronis doesn’t have any. Hugo didn’t have any. Darwin didn’t have any. Lamarck didn’t have any. We’ve been sitting in the dark an awful long time listening to this crowd promise that some day somebody will “shed light on evolution.” Would you spare a dime for their paradigm? Don’t buy their promissory notes; not even your great-great-grandkids can expect to collect.(Visited 19 times, 1 visits today)FacebookTwitterPinterestSave分享0
For over 40 years, the World Economic Forum has brought together global leaders in government, civil society and business. This year’s annual meeting in Davos starts on 17 January. South Africa will be participating again.Brand South Africa reporterThe 47th World Economic Forum (WEF) Annual Meeting in Davos-Klosters, Switzerland, takes place from 17 to 20 January under the theme “Responsive and Responsible Leadership”.How to follow Davos 2017 https://t.co/UKaPmjlieK #wef17 pic.twitter.com/oASGyVtR43— World Economic Forum (@wef) January 8, 2017South Africa will be participating in the talks once again and will position itself as “Open for Business”.Speaking to CNBC Africa about the meeting, Lungisa Fuzile, the director-general in the National Treasury, said: “South Africa has many opportunities; it has many strengths. We need to focus on our strengths as we grapple with our challenges, and build on those strengths.”He said the country’s macro-economic management was among the soundest in the world.South Africa first attended WEF Davos in 2009. Over the years the country’s focus has been and continues to be:Profiling the country as an attractive investment destination;Highlighting the significance and successes of the National Development Plan;Positioning South Africa as a positive influencer on global agendas, and;Headlining the strengths of its institutions and systems and as a thriving democracy.History of WEF DavosWEF Davos brings together various sectors, such as business, civil society and government to discuss and propose solutions to global challenges.“[It] remains the foremost creative force for engaging the world’s top leaders in collaborative activities to shape the global, regional and industry agendas at the beginning of each year,” reads the forum’s website.“For over four decades, the World Economic Forum’s mission – improving the state of the world – has driven the design and development of the annual meeting programme.”It began in January 1971 as the first European Management Symposium, founded by Professor Klaus Schwab. By 1987, it had transformed into the WEF and “sought to broaden its vision to include providing a platform for dialogue”, reads the website.The annual meeting became a place of global political milestones, such as the first ministerial meeting between North Korea and South Korea in 1989; and the first joint appearance in 1992 outside South Africa of former South African president FW de Klerk, Nelson Mandela and Inkatha Freedom Party’s Chief Mangosuthu Buthelezi.“In 2015, the forum was formally recognised as an international organisation,” reads the website. “It is now on the next phase of its journey as the global platform for public-private co-operation.”Would you like to use this article in your publication or on your website? See Using Brand South Africa material.
Share Facebook Twitter Google + LinkedIn Pinterest Do you work for the township, county, city, or state government? Apple Farm Service appreciates everything you do to keep our streets, parks, neighborhoods, and communities maintained and safe. They would like to say thank you with a special day just for you.Apple Farm Service is excited to announce their first annual Local Government Appreciation Days. Anyone who works for any level of government (whether local, state, or federal) are invited to join them!Mark your calendars for these dates:• Covington Store, 10120 West Versailles Rd., Covington. Thursday, June 6, 10 a.m. untill 3 p.m.• Mechanicsburg Store, 12446 East State Rt 29, Mechanicsburg, Thursday, June 13, 10 a.m. until 3 p.m.Government employees can stop by for prize giveaways, product demonstrations, test drives, and equipment education. Apple Farm Service will also be firing up the grill for a cook-out lunch.Product specialists will be on site to provide equipment education, lessons to find the best deals with government bidding and purchasing programs, and product demonstrations. Mowers, tractors, skid steers, attachments, and everything grounds care and construction will be on display.This free event is a small token of appreciation for everything you do for our communities.