Tag: 上海千花网AS

Posted in votwpslwaksb

Angering animal welfare activists Mauritius invites primate research labs to set up

first_img Mauritius has exported monkeys for research since the company Bioculture began shipping the animals three decades ago. Today, the country is the second-largest source, after China, of long-tailed macaques, familiar to scientists as cynomolgus monkeys. In 2016, its breeders exported 8245 animals to North America and Europe—nearly half of them to the United States (see chart, below). The captive-bred Mauritian macaques are valued because, as a result of their island isolation, they are free of simian viruses including B virus, which in rare cases has infected lab workers after bites, leaving them brain-damaged or dead. The animals’ genetic makeup—in particular their patterns of expression of certain cell-surface proteins—also makes them useful models for studies of HIV.By now, however, Air France is the only commercial carrier still willing to fly nonhuman primates bound for research labs. And the pressure continues: In January, the former model, singer, and actress Brigitte Bardot wrote to Air France asking that it stop flying research-bound macaques from Mauritius to Paris and beyond, calling it a “shameful business.””The breeders are having problems placing the monkeys that they breed. So they have encouraged the government to allow the setup of labs,” says Nick Palmer, a former member of U.K. parliament and information technology manager at the drug company Novartis. Now a policy adviser for Cruelty Free International, Palmer flew to the island last month to lobby National Assembly members to oppose the new regulations. Monkey business Mauritius is the world’s second-largest exporter of long-tailed macaques, a laboratory favorite. Angering animal welfare activists, Mauritius invites primate research labs to set up shop Click to view the privacy policy. Required fields are indicated by an asterisk (*) Country * Afghanistan Aland Islands Albania Algeria Andorra Angola Anguilla Antarctica Antigua and Barbuda Argentina Armenia Aruba Australia Austria Azerbaijan Bahamas Bahrain Bangladesh Barbados Belarus Belgium Belize Benin Bermuda Bhutan Bolivia, Plurinational State of Bonaire, Sint Eustatius and Saba Bosnia and Herzegovina Botswana Bouvet Island Brazil British Indian Ocean Territory Brunei Darussalam Bulgaria Burkina Faso Burundi Cambodia Cameroon Canada Cape Verde Cayman Islands Central African Republic Chad Chile China Christmas Island Cocos (Keeling) Islands Colombia Comoros Congo Congo, the Democratic Republic of the Cook Islands Costa Rica Cote d’Ivoire Croatia Cuba Curaçao Cyprus Czech Republic Denmark Djibouti Dominica Dominican Republic Ecuador Egypt El Salvador Equatorial Guinea Eritrea Estonia Ethiopia Falkland Islands (Malvinas) Faroe Islands Fiji Finland France French Guiana French Polynesia French Southern Territories Gabon Gambia Georgia Germany Ghana Gibraltar Greece Greenland Grenada Guadeloupe Guatemala Guernsey Guinea Guinea-Bissau Guyana Haiti Heard Island and McDonald Islands Holy See (Vatican City State) Honduras Hungary Iceland India Indonesia Iran, Islamic Republic of Iraq Ireland Isle of Man Israel Italy Jamaica Japan Jersey Jordan Kazakhstan Kenya Kiribati Korea, Democratic People’s Republic of Korea, Republic of Kuwait Kyrgyzstan Lao People’s Democratic Republic Latvia Lebanon Lesotho Liberia Libyan Arab Jamahiriya Liechtenstein Lithuania Luxembourg Macao Macedonia, the former Yugoslav Republic of Madagascar Malawi Malaysia Maldives Mali Malta Martinique Mauritania Mauritius Mayotte Mexico Moldova, Republic of Monaco Mongolia Montenegro Montserrat Morocco Mozambique Myanmar Namibia Nauru Nepal Netherlands New Caledonia New Zealand Nicaragua Niger Nigeria Niue Norfolk Island Norway Oman Pakistan Palestine Panama Papua New Guinea Paraguay Peru Philippines Pitcairn Poland Portugal Qatar Reunion Romania Russian Federation Rwanda Saint Barthélemy Saint Helena, Ascension and Tristan da Cunha Saint Kitts and Nevis Saint Lucia Saint Martin (French part) Saint Pierre and Miquelon Saint Vincent and the Grenadines Samoa San Marino Sao Tome and Principe Saudi Arabia Senegal Serbia Seychelles Sierra Leone Singapore Sint Maarten (Dutch part) Slovakia Slovenia Solomon Islands Somalia South Africa South Georgia and the South Sandwich Islands South Sudan Spain Sri Lanka Sudan Suriname Svalbard and Jan Mayen Swaziland Sweden Switzerland Syrian Arab Republic Taiwan Tajikistan Tanzania, United Republic of Thailand Timor-Leste Togo Tokelau Tonga Trinidad and Tobago Tunisia Turkey Turkmenistan Turks and Caicos Islands Tuvalu Uganda Ukraine United Arab Emirates United Kingdom United States Uruguay Uzbekistan Vanuatu Venezuela, Bolivarian Republic of Vietnam Virgin Islands, British Wallis and Futuna Western Sahara Yemen Zambia Zimbabwe By Meredith WadmanMay. 3, 2017 , 12:15 PM OLGA KHOROSHUNOVA/ALAMY STOCK PHOTO Sign up for our daily newsletter Get more great content like this delivered right to you! Country The persistent fight by animal welfare activists to end nonhuman primate research has found its way to Mauritius, an island in the Indian Ocean two-thirds the size of Rhode Island. In the 1700s, Dutch and Portuguese seafarers introduced the long-tailed macaque to the island, where the animals thrived and, in recent decades, formed the basis of an export industry supplying biomedical labs in the developed world. Now, Mauritius has decided to get into the business of nonhuman primate experimentation itself even as such work is becoming increasingly constrained in North America and Europe. Last month the move touched off a heated debate in Mauritius’s National Assembly about whether the government could adequately protect the macaques used in research and whether the new industry might endanger a far bigger lifeline for the island—tourism.The debate is reverberating overseas. Activists, led by London-based Cruelty Free International, see the influence of Mauritius’s five monkey breeding companies behind the government’s February step allowing licenses to be issued for local research on island-bred macaques. (The new regulations also allow rabbit and rodent studies.) They contend that the companies are alarmed by a successful, high-pressure campaign to discourage commercial airlines from flying nonhuman primates from source countries such as Mauritius to research centers—and are trying to hedge their bets. The London group also argues that the new regulations, which amend the country’s Animal Welfare Act, are invalid because they don’t further the purpose of the original legislation.Some scientists see it differently. Tipu Aziz, a neuroscientist at the University of Oxford in the United Kingdom who says he was obliged by stringent U.K. animal welfare regulations to abandon studies of Parkinson’s disease in long-tailed macaques, commends Mauritius’s effort as a “forward-thinking” attempt to build up its biotech sector. But, he says, “They’ve got a lot of work ahead of them” to attract drug studies and basic research, noting that China has already established sophisticated nonhuman primate research centers that are attractive to Western customers. Mauritius’s breeders established colonies from wild-caught macaques. Email DATA: CITES TRADE DATABASE But Nada Padayatchy, development and liaison manager at Bioculture, says the government’s decision “is not based on the perceived difficulty of exporting the animals.” She says the move into experimentation is a logical step for a country that already aspires to be a biomedical hub. A biomedical contract research organization, Centre International de Développement Pharmaceutique, was established in Mauritius in 2004, and in 2011, the country began promoting itself as a clinical trial destination. It has since lured the drug company Merck to conduct diabetes drug studies in local children and adults.”We see [animal experimentation] as a natural evolution and a logical follow-up” to the move into human clinical trials, Padayatchy says. The hoped-for outcome: new collaborations and partnerships with drug companies and contract research organizations. She also argues that bringing the research to the animals rather than vice versa is far easier on them, and better, too, for the research, than transporting them to destinations half a world away.Although no customers have materialized yet for the country’s foray into animal research, Mauritius does have the blessing of the large auditing firm KPMG, which last year declared the country “the most accommodative business environment in Africa, with high levels of economic freedom and low tax rates.”But both academic and industry scientists say that luring offshore researchers will be a challenge for Mauritius. One senior U.S. pharmaceutical executive, who would speak only if kept anonymous, wondered whether the tiny nation will be able to meet the good laboratory practices (GLPs) required of facilities that test drugs intended for humans in macaques: “GLP is a really big deal. A lot of things have to be highly controlled and monitored,” the unnamed executive says. “Results can’t be influenced by ‘The power went out for 6 hours,’ or ‘There’s a typhoon coming and we’re going to have to lock down the facility.’”Some members of Mauritius’s National Assembly worry about safeguards for the animals. During floor debate last month, one member, Paul Bérenger, asked who would ensure that the animals would be protected at European Union standards. Another, Rajesh Bhagwan, asked whether public transparency about the nature and conduct of the experiments would be guaranteed—and what the impact would be on the islands’ all-important tourism industry, which grew by 11% in 2015 and 2016.The government is undeterred. “We are supporting this [experimentation] industry,” Minister of Agro-Industry and Food Security Mahen Kumar Seeruttun told the National Assembly. The government, he added, thinks it “wise.”last_img read more

Continue Reading Angering animal welfare activists Mauritius invites primate research labs to set up